Oxford/AstraZeneca in ‘mix-match’ COVID-19 vaccine trial with Russia’s Sputnik


PTI, Dec 12, 2020, 5:46 PM IST

London: The Oxford University and AstraZeneca COVID-19 vaccine, currently awaiting regulatory approvals, is set to be used for a “mix and match” trial with Russia’s Sputnik vaccine against the novel coronavirus, according to UK media reports.

The two sets of experts are to join forces to explore if a combination of the two jabs, both using a benign virus called adenovirus, could prove effective in offering people long-term protection against COVID-19.

According to The Times, the idea is that by using different vaccines, each shot may prompt a stronger immune response.

AstraZeneca, the bio-pharmaceutical major which produces the Oxford University’s vaccine, has agreed to collaborate with Sputnik in a deal apparently sealed after an offer was made on Twitter, the newspaper said.

Early results from the final-stage trial of the Sputnik vaccine showed it was 90 per cent effective and findings that involved more cases with the Oxford vaccine indicated it was 62 per cent effective in one regimen and 90 per cent in another.

“The new chapter of vaccine co-operation has started today. We made an offer and AstraZeneca accepted it,” claimed Sputnik’s Twitter account.

AstraZeneca confirmed that it would collaborate with the Gamaleya Research Institute, which designed the Sputnik vaccine.

“Combinations of different COVID-19 vaccines may be an important step in generating wider protection,” it said in a statement.

Both vaccines use adenovirus to infect cells and trick them into making the spike protein of the coronavirus.

Russia has already begun its vaccination campaign but it has had a low uptake so far. The AstraZeneca collaboration is expected to help increase confidence in the Sputnik vaccine.

Mixing and matching different vaccines is known as a heterologous prime-boost and has been used in vaccination programmes against other diseases.

Udayavani is now on Telegram. Click here to join our channel and stay updated with the latest news.

Top News

Praveen Nettaru case: Police arrest two more persons

Chennai lad Pranav becomes India’s 75th Grandmaster

All restrictions relaxed; Sec 144 extended: Dakshina Kannada DC

Gold Rush: Boxers Nikhat Zareen, Amit Panghal, Nitu grab maiden CWG gold medals

Tree falls on bike-borne man, dies on spot

Mumbai: Civic hospital doctors save worker’s life by surgically removing steel rod from chest

One held with 295 turtles in Lucknow


Related Articles More

COVID-19: India records 19,400 new cases, 49 deaths

Karnataka reports 1,886 new COVID-19 cases, one death

Karnataka reports 1,456 new COVID-19 cases

COVID: Risk of diabetes and heart disease is higher after infection – but maybe only temporarily

Karnataka reports 1,478 new COVID-19 cases

MUST WATCH

NEWS BULLETIN 08-08-2022

Commonwealth Games medal winner Gururaj Poojari Grand welcome in Udupi

Mysuru Dasara 2022: Gajapayana flagged off from Nagarahole National Park

Road Covers Flood water at teerthahalli

Health, Earth, & We Can All Be Well With Natural Fertilizer |


Latest Additions

Praveen Nettaru case: Police arrest two more persons

Chennai lad Pranav becomes India’s 75th Grandmaster

All restrictions relaxed; Sec 144 extended: Dakshina Kannada DC

Gold Rush: Boxers Nikhat Zareen, Amit Panghal, Nitu grab maiden CWG gold medals

Fake loan App racket: Mumbai Police take 3 accused on remand

Thanks for visiting Udayavani

You seem to have an Ad Blocker on.
To continue reading, please turn it off or whitelist Udayavani.