Pesticide exposure can increase the risk of Parkinson’s disease in individuals


Team Udayavani, Apr 11, 2024, 11:00 AM IST

Parkinson’s disease (PD) is a common degenerative condition of Brain. It commonly affects the elderly, although no age is exempt. PD is a growing epidemic due to ageing population across the globe. The primary change noted in PD patients is the progressive loss of dopamine producing cells in a specific area of Brain called Substantia nigra. What triggers this cell loss? and why only certain individuals are affected? These questions remain unanswered at present. It is proposed that a combination of genetic and environmental factors play a role.

Parkinson’s is a slowly developing condition and the cell loss in brain often starts several years prior to the onset of symptoms. It is difficult to ascertain the causal factors present in the nature over such a long period; often several factors can come together to produce the disease. We understand about these environmental culprits through retrospective and observational studies, which are often prone to bias. However, these studies have consistently shown that certain factors like smoking and coffee are protective, while others such as pesticide exposure increases the risk of developing PD.

The role of pesticides is important in an agrarian country like India. Although the risk is high among farmers who are constantly exposed to these pesticides, an increased risk was noted even with household exposure such as gardening or using insecticides (eg: rat killers). Interestingly, some studies have highlighted an increasing risk of PD with consumption of well water in rural areas, possibly due to contamination with pesticides. Among the pesticides, herbicides and insecticides like paraquat carry a higher risk compared to fungicides. Scientists are using innovative methods like Geographic Information System and satellite remote sensing data to calculate pesticide exposure and the risk of PD.

A latest study has analyzed the data of 21.5 million people enrolled with medicare and noted a consistent relationship with 14 of the 65 studied pesticides. Among these herbicides like simazine, atrazine and organochlorides like lindane carried the highest risk.

Pesticide exposure is also implicated in other brain disorders like Alzheimer’s dementia, motor neuron disease, childhood developmental delay among others. In recent times, non-profit organization like Michael J Fox foundation is actively engaged with the government to ban certain pesticides like Paraquat.

Dr. Mirza Masoom Abbas, Consultant – Neurologist, Manipal Hospital Yeshwanthpur and Millers Road

Udayavani is now on Telegram. Click here to join our channel and stay updated with the latest news.

Top News

Gangster Chhota Rajan sentenced to life imprisonment for murder of Mumbai hotelier Jaya Shetty

God and meditation PM’s private affair, why should we interfere; asks D K Shivakumar

Udupi: BJP expels four office bearers for anti-party activities

Illegal money transfer case Minister B Nagendra will be summoned, says Shivakumar

Twenty one killed, 47 injured as bus falls into gorge in Jammu

IndiGo derosters 6 crew members in connection with Delhi-Varanasi flight bomb scare incident

Delhi CM Kejriwal faces health crisis amid ED custody

Related Articles More

Kasturba Hospital, Manipal Recognized as One of India’s Most Trusted IVF and Fertility Centers by Insights Care

Humid conditions and asthma flare-ups – understanding the connection

Kerala students attempt to make ‘green coffee’ powder popular

Depression, schizophrenia and bipolar disorder linked with ancient viral DNA in our genome – new research

Does ‘whining’ really make you happier? A therapist gives his verdict

MUST WATCH

Shivamogga

Les Saveurs institute and cafe

Peacock rescued from well

Popular Guruprasad Restaurant

Haralukote Shri Anjaneya Swamy |Udayavani


Latest Additions

Gangster Chhota Rajan sentenced to life imprisonment for murder of Mumbai hotelier Jaya Shetty

Akhilesh Yadav mocks Modi’s meditation trip amid poll campaign

God and meditation PM’s private affair, why should we interfere; asks D K Shivakumar

Vice President Dhankhar visits Neem Karoli Baba Ashram

Udupi: BJP expels four office bearers for anti-party activities

Thanks for visiting Udayavani

You seem to have an Ad Blocker on.
To continue reading, please turn it off or whitelist Udayavani.