Remdesivir becomes first drug to be fully approved for COVID-19 by US: All you need to know


Team Udayavani, Oct 23, 2020, 1:13 PM IST

The US Food and Drug Administration on Thursday approved Gilead’s antiviral drug remdesivir for treating patients hospitalised with COVID-19, making it the first and only drug approved for the disease in the US.

Remdesivir was given to President Donald Trump this month when he was diagnosed with COVID-19. It was originally developed as a treatment for Ebola and Hepatitis C.

Remdesivir was developed to treat Ebola disease caused by an RNA virus. Now, Gilead discovered that the drug has antiviral activity in vitro against pathogens that cause MERS and SARS, which are coronaviruses and structurally similar to SARS-CoV-2 that causes COVID-19, an RNA virus.

Remdesivir is thought to interfere with the mechanism that certain viruses, including the new coronavirus, use to make copies of themselves.

According to FirstPost, Remdesivir is a nucleoside analogue. Studies show that it competes with ATP (adenosine triphosphate) during the production of viral RNA.

Viruses are intracellular parasites. Once they get inside healthy cells, they use the machinery and materials from these cells to make copies of their own nucleic acid. RNA or ribonucleic acid is the genetic material of SARS-CoV-2.

Every RNA is made of a series of four nucleotide bases arranged in various ways to code for specific characters or make specific proteins. These bases include ATP, GTP, CTP and UTP.

An enzyme called RNA polymerase makes new RNA copies which are then used to make new viruses. Remdesivir, when it gets integrated in place of ATP during the formation of RNA, completely halts the replication process. No replication means no new RNA and no new virus.

Udayavani is now on Telegram. Click here to join our channel and stay updated with the latest news.

Top News

4 health dept officials to monitor screening at international airports in TN

Bihar: Village votes for dead candidate to honour dying wish. He won!

PM files in aircraft worth Rs 8,000 cr to address rally but can’t waive farmers’ debt: Priyanka

Majority of Indians surveyed want govt to reconsider decision on international flights

Never saw myself as white ball specialist: Axar Patel

2 Hizbul Mujahideen terror associates held in Pulwama

High alert: World scurries to contain new COVID variant


Related Articles More

Top UK scientist says new COVID-19 variant Omicron ‘not a disaster’, vaccination likely to protect

COVID death data can be shared to make it look like vaccines don’t work, or worse – but that’s not the whole picture

The hunt for coronavirus variants: how the new one was found and what we know so far

Experts allay Covaxin concerns, say 50 pc effectiveness against Delta-driven Covid surge not bad

Demographic shift: NFHS survey finds more women than men in India

MUST WATCH

Gopal Naik Alevoor | How to do Vermicomposting Business in India and its uses

ನಂಬಿ ಬಂದವರ ಸರ್ವ ಕಷ್ಟ ಪರಿಹರಿಸುವ ತಾಯಿ ಚಾಮುಂಡೇಶ್ವರಿ

NEWS BULLETIN 27-11-2021

Kustagi Viral Video

Wild boar creates havoc at car showroom; Video goes viral


Latest Additions

4 health dept officials to monitor screening at international airports in TN

Bihar: Village votes for dead candidate to honour dying wish. He won!

PM files in aircraft worth Rs 8,000 cr to address rally but can’t waive farmers’ debt: Priyanka

Majority of Indians surveyed want govt to reconsider decision on international flights

Never saw myself as white ball specialist: Axar Patel

Thanks for visiting Udayavani

You seem to have an Ad Blocker on.
To continue reading, please turn it off or whitelist Udayavani.